GTX04319-PRO
Mouse TGF beta 1 protein, His tag (active)
Cannot supply to this region.
- SKU:
- GTX04319-PRO
- Application:
- WB, FuncS, Neutralisation
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles.
- Supplier:
- Genetex
- Buffer:
- Reconstitute in 20mM Tris, 150mM NaCl pH8.0 to a concentration of 0.1-1.0 mg/mL. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl pH8.0, 0.05% sarcosyl, 5% trehalose, 5% Proclin300.
- Immunogen:
- transforming growth factor, beta 1
- Species:
- Mouse
- Uniprot:
- P04202
- Synonyms:
- TGF-beta;TGF-beta1;Tgfb;Tgfb-1;TGFbeta;TGFbeta1;transforming growth factor beta-1 proprotein
- Extra Details:
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer. [provided by RefSeq, Aug 2016]
- Shipping Conditions:
- Blue Ice