GTX04258
AIRE antibody
Cannot supply to this region.
- SKU:
- GTX04258
- Additional Names:
- autoimmune regulator , AIRE1 , APECED , APS1 , APSI , PGA1
- Application:
- WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% sodium azide.
- Immunogen:
- Synthetic peptide, corresponding to amino acids 101-150 of Human AIRE.
- Uniprot:
- O43918
- Synonyms:
- AIRE1;APECED;APS1;APSI;autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein;autoimmune regulator;PGA1
- Extra Details:
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Shipping Conditions:
- Blue Ice