GTX03798
PTPD1 antibody
Cannot supply to this region.
- SKU:
- GTX03798
- Additional Names:
- protein tyrosine phosphatase non-receptor type 21 , PTPD1 , PTPRL10
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Dialysis
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.09% sodium azide.
- Immunogen:
- This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
- Uniprot:
- Q16825
- Synonyms:
- dJ1175B15.2 (protein tyrosine phosphatase, non-receptor type 21);protein-tyrosine phosphatase D1;PTPD1;PTPRL10;tyrosine-protein phosphatase non-receptor type 21
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice