Human EPO protein (active)

Cannot supply to this region.

SKU:: GTX03793-PRO
Additional Names:: erythropoietin , DBAL , ECYT5 , EP , MVCD2
Application:: FuncS
Physical State:: Lyophilized
Storage Conditions:: -20[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: Batch dependent (please contact us for details)
Immunogen:: erythropoietin
Species:: Human
Uniprot:: P01588
Synonyms:: DBAL;ECYT5;EP;epoetin;erythropoietin;MVCD2
Extra Details:: This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]