GTX03707
Gremlin 1 antibody
Cannot supply to this region.
- SKU:
- GTX03707
- Additional Names:
- gremlin 1, DAN family BMP antagonist , Cktsf1b1 , Drm , Grem , ld
- Application:
- WB, IHC-P
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Affinity Purified; Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.09% sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 147-175 amino acids from the C-terminal region of mouse GREMLIN.
- Uniprot:
- O70326
- Synonyms:
- Cktsf1b;Cktsf1b1;cysteine knot superfamily 1, BMP antagonist 1;down-regulated in Mos-transformed cells protein;down-regulated in v-mos-transformed cells;Dr;Drm;gre;Grem;gremlin-1;ld
- Extra Details:
- Enables receptor ligand activity; transmembrane receptor protein tyrosine kinase activator activity; and vascular endothelial growth factor receptor 2 binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; nephron epithelium morphogenesis; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of branching involved in ureteric bud morphogenesis; and regulation of signal transduction. Located in extracellular space. Colocalizes with cell surface. Is expressed in several structures, including embryo mesenchyme; limb bud; neural ectoderm; sensory organ; and skeleton. Orthologous to human GREM1 (gremlin 1, DAN family BMP antagonist). [provided by Alliance of Genome Resources, Apr 2022]
- Shipping Conditions:
- Blue Ice