Caldesmon antibody [hHCD]

Cannot supply to this region.

SKU:: GTX03317
Additional Names:: caldesmon 1 , CDM , H-CAD , HCAD , L-CAD , LCAD , NAG22
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: BALB/C mice were injected with human uterus smooth muscle extract.
Clone:: hHCD
Uniprot:: Q05682
Synonyms:: caldesmon;CDM;H-CAD;HCAD;L-CAD;LCAD;NAG22;testis secretory sperm-binding protein Li 227n
Extra Details:: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]