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GTX03316

Ku70 antibody [H-6]

Cannot supply to this region.

SKU:
GTX03316
Additional Names:
X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA
Application:
IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:
Ku-(p70) is a mouse monoclonal antibody specific for an epitope mapping between amino acids 583-608 at the C-terminus of KU70 of human origin.
Clone:
H-6
Uniprot:
P12956
Synonyms:
5'-deoxyribose-5-phosphate lyase Ku70;5'-dRP lyase Ku70;70 kDa subunit of Ku antigen;ATP-dependent DNA helicase 2 subunit 1;ATP-dependent DNA helicase II 70 kDa subunit;ATP-dependent DNA helicase II, 70 kDa subunit;CTC box binding factor 75 kDa subunit;CTC box-binding factor 75 kDa subunit;CTC75;CTCBF;DNA repair protein XRCC6;G22P1;Ku autoantigen p70 subunit;Ku autoantigen, 70kDa;KU70;lupus Ku autoantigen protein p70;ML8;thyroid autoantigen 70kD (Ku antigen);thyroid autoantigen 70kDa (Ku antigen);Thyroid-lupus autoantigen;thyroid-lupus autoantigen p70;TLAA;X-ray repair complementing defective repair in Chinese hamster cells 6;X-ray repair cross-complementing protein 6
Extra Details:
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice