C4d antibody [C4D204]

Cannot supply to this region.

SKU:: GTX03302
Additional Names:: complement C4B (Chido blood group) , C4B1 , C4B12 , C4B2 , C4B3 , C4B5 , C4BD , C4B_2 , C4F , CH , CO4 , CPAMD3
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.1% BSA, 0.05% Sodium azide.
Immunogen:: A recombinant fragment specific to Complement 4d
Clone:: C4D204
Uniprot:: P0C0L4, P0C0L5
Synonyms:: acidic C4;acidic complement C4;basic complement C4;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2;C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3;C4;C4A anaphylatoxin;C4A2;C4A3;C4A4;C4A6;C4AD;C4B_2;C4B1;C4B12;C4B2;C4B3;C4B5;C4BD;C4F;C4S;CH;Chido form of C4;CO4;complement C4-A;complement C4-B;complement C4-B-like;complement C4B1a;complement component 4A (Rodgers blood group);complement component 4B (Chido blood group);CPAMD2;CPAMD3;MHC class III region complement;RG;Rodgers form of C4
Extra Details:: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice