SOCS2 antibody [GT1326]

Cannot supply to this region.

SKU:: GTX03238
Additional Names:: suppressor of cytokine signaling 2 , CIS2 , Cish2 , SOCS-2 , SSI-2 , SSI2 , STATI2
Application:: WB, IHC-P, IF, ICC
Concentration:: 2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human SOCS2.
Clone:: GT1326
Uniprot:: O14508
Synonyms:: CIS-2;CIS2;Cish2;cytokine-inducible SH2 protein 2;SOCS-2;SSI-2;SSI2;STAT-induced STAT inhibitor 2;STATI2;suppressor of cytokine signaling 2
Extra Details:: This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Shipping Conditions:: Blue Ice