FHIT antibody [GT1240]

Cannot supply to this region.

SKU:: GTX02837
Additional Names:: fragile histidine triad , AP3Aase , FRA3B
Application:: WB
Concentration:: 1.59 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Rat
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human FHIT
Clone:: GT1240
Uniprot:: P49789
Synonyms:: AP3A hydrolase;AP3Aase;bis(5'-adenosyl)-triphosphatase;diadenosine 5',5'''-P1,P3-triphosphate hydrolase;dinucleosidetriphosphatase;FRA3B;Fragile histidine triad protein
Extra Details:: The protein encoded by this gene is a P1-P3-bis(5'-adenosyl) triphosphate hydrolase involved in purine metabolism. This gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. The encoded protein is also a tumor suppressor, as loss of its activity results in replication stress and DNA damage. [provided by RefSeq, Aug 2017]