NOTCH1 antibody [GT1224]

Cannot supply to this region.

SKU:: GTX02821
Additional Names:: notch receptor 1 , AOS5 , AOVD1 , TAN1 , hN1
Application:: WB, IP
Concentration:: 2 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C concentrated solution. Aliquot. Avoid freeze/thaw cycles., -20[o]C 50% glycerol. Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from human Notch1
Clone:: GT1224
Uniprot:: P46531
Synonyms:: AOS5;AOVD1;hN1;neurogenic locus notch homolog protein 1;notch 1;Notch homolog 1, translocation-associated;TAN1;translocation-associated notch protein TAN-1
Extra Details:: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in this gene are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma. [provided by RefSeq, Jan 2016]

Shipping Conditions:: Blue Ice