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  2. Monoclonal

GTX02661

Cytokeratin 6a antibody [rKRT6A/2100]

Cannot supply to this region.

SKU:
GTX02661
Additional Names:
keratin 6A , CK-6C , CK-6E , CK6A , CK6C , CK6D , K6A , K6C , K6D , KRT6C , KRT6D , PC3
Application:
IHC-P
Concentration:
200 ug/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
protein a/g purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:
Recombinant full-length human Cytokeratin 6A (KRT6A) protein
Clone:
rKRT6A/2100
Uniprot:
P02538
Synonyms:
CK-6C;CK-6E;CK6A;CK6C;CK6D;cytokeratin 6A;cytokeratin 6C;cytokeratin 6D;Cytokeratin-6A;Cytokeratin-6D;K6A;K6C;K6D;keratin 6A, , type II;keratin 6A, type II;Keratin-6A;keratin, epidermal type II, K6A;keratin, type II cytoskeletal 6A;KRT6C;KRT6D;PC3;type-II keratin Kb6
Extra Details:
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Oct 2014]
Shipping Conditions:
Blue Ice