Skip to content

View Spec Sheet

open_in_new
  1. Shop all
  2. Monoclonal

GTX02652

Insulin Receptor alpha antibody [INSR/2277R]

Cannot supply to this region.

SKU:
GTX02652
Additional Names:
insulin receptor , CD220 , HHF5
Application:
IHC-P
Concentration:
200 ug/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
protein a/g purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:
Recombinant fragment of extracellular domain of human Insulin Receptor alpha
Clone:
INSR/2277R
Uniprot:
P06213
Synonyms:
CD220;HHF5;insulin receptor;IR
Extra Details:
This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Shipping Conditions:
Blue Ice