Caldesmon antibody [CALD1/1424R]

Cannot supply to this region.

SKU:: GTX02598
Additional Names:: caldesmon 1 , CDM , H-CAD , HCAD , L-CAD , LCAD , NAG22
Application:: IHC-P
Concentration:: 200 ug/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Rat
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant human full-length CALD1 protein
Clone:: CALD1/1424R
Uniprot:: Q05682
Synonyms:: caldesmon;CDM;H-CAD;HCAD;L-CAD;LCAD;NAG22;testis secretory sperm-binding protein Li 227n
Extra Details:: This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]