AMACR antibody [rAMACR/1864]

Cannot supply to this region.

SKU:: GTX02585
Additional Names:: alpha-methylacyl-CoA racemase , AMACRD , CBAS4 , P504S , RACE , RM
Application:: WB, IHC-P
Concentration:: 200 ug/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 0.05% BSA, 0.05% Sodium azide.
Immunogen:: Recombinant human AMACR protein fragment (around aa 297-394)
Clone:: rAMACR/1864
Uniprot:: Q9UHK6
Synonyms:: 2-methylacyl-CoA racemase;alpha-methylacyl-CoA racemase;AMACRD;CBAS4;P504S;RACE;RM
Extra Details:: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]