GTX02538
Growth hormone Receptor antibody
Cannot supply to this region.
- SKU:
- GTX02538
- Additional Names:
- growth hormone receptor , GHBP , GHIP
- Application:
- Flow Cytometry, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Porcine, Rat, Ovine
- Buffer:
- Aqueous buffered solution, 1% BSA, 50% Glycerol, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide derived from human GHR (290-340/638).
- Uniprot:
- P10912
- Synonyms:
- GH receptor;GHBP;GHIP;growth hormone binding protein;growth hormone receptor;mutant growth hormone receptor;serum binding protein;somatotropin receptor;truncated growth hormone receptor
- Extra Details:
- This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
- Shipping Conditions:
- Blue Ice