Utrophin antibody [DRP3/20C5]

Cannot supply to this region.

SKU:: GTX01977
Additional Names:: utrophin , DMDL , DRP , DRP1
Application:: IHC-Fr
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Human, Rat
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Fusion protein containing the first 261 amino acids of the published DMDL gene sequence.
Clone:: DRP3/20C5
Uniprot:: P46939
Synonyms:: DMDL;DRP;DRP1;dystrophin-related protein 1;utrophin
Extra Details:: This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice