Caveolin 1 antibody [4D6]

Cannot supply to this region.

SKU:: GTX01969
Additional Names:: caveolin 1 , BSCL3 , CGL3 , LCCNS , MSTP085 , PPH3 , VIP21
Application:: WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Prokaryotic recombinant protein corresponding to the N-terminus domain of the human caveolin-1 molecule.
Clone:: 4D6
Uniprot:: Q03135
Synonyms:: BSCL3;caveolin 1, caveolae protein, 22kDa;caveolin-1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;PPH3;VIP21
Extra Details:: The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010]