CD163 antibody [10D6]

Cannot supply to this region.

SKU:: GTX01963
Additional Names:: CD163 molecule , M130 , MM130 , SCARI1
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Prokaryotic recombinant protein corresponding to domains 1 to 4 of the N-terminal region of the CD163 molecule.
Clone:: 10D6
Uniprot:: Q86VB7
Synonyms:: hemoglobin scavenger receptor;M130;macrophage-associated antigen;MM130;SCARI1;scavenger receptor cysteine-rich type 1 protein M130
Extra Details:: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]