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  2. Monoclonal

GTX01952

NKX2.1 antibody [SPT24]

Cannot supply to this region.

SKU:
GTX01952
Additional Names:
NK2 homeobox 1 , BCH , BHC , NK-2 , NKX2.1 , NKX2A , NMTC1 , T/EBP , TEBP , TITF1 , TTF-1 , TTF1
Application:
IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Unpurified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:
Prokaryotic recombinant protein corresponding to a 123 amino acid fragment of the N-terminal region of the TTF-1 molecule.
Clone:
SPT24
Uniprot:
P43699
Synonyms:
BCH;BHC;homeobox protein NK-2 homolog A;homeobox protein Nkx-2.1;NK-2;NK-2 homolog A;NKX2.1;NKX2A;NMTC1;T/EBP;TEBP;thyroid nuclear factor 1;thyroid transcription factor 1;thyroid-specific enhancer-binding protein;TITF1;TTF-1;TTF1
Extra Details:
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription. [provided by RefSeq, Feb 2014]
Shipping Conditions:
Blue Ice