p57 Kip2 antibody [25B2]

Cannot supply to this region.

SKU:: GTX01862
Additional Names:: cyclin dependent kinase inhibitor 1C , BWCR , BWS , KIP2 , WBS , p57 , p57Kip2
Application:: WB, IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Unpurified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tissue culture supernatant, 0.09% Sodium azide.
Immunogen:: Prokaryotic recombinant antigen corresponding to a 116 amino acid region of the N-terminus of the p57 protein.
Clone:: 25B2
Uniprot:: P49918
Synonyms:: BWCR;BWS;cyclin-dependent kinase inhibitor 1C;cyclin-dependent kinase inhibitor 1C (p57, Kip2);cyclin-dependent kinase inhibitor p57;KIP2;p57;p57Kip2;WBS
Extra Details:: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]