Granzyme B antibody [ZM66]

Cannot supply to this region.

SKU:: GTX01704
Additional Names:: granzyme B , C11 , CCPI , CGL-1 , CGL1 , CSP-B , CSPB , CTLA1 , CTSGL1 , HLP , SECT
Application:: IHC-P
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
Immunogen:: Recombinant human GZMB protein fragment (around aa 73-187)
Clone:: ZM66
Uniprot:: P10144
Synonyms:: C11;cathepsin G-like 1;CCPI;CGL-1;CGL1;CSP-B;CSPB;CTLA-1;CTLA1;CTSGL1;cytotoxic serine protease B;cytotoxic T-lymphocyte proteinase 2;fragmentin 2;Fragmentin-2;granzyme B;granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1);Granzyme-2;HLP;human lymphocyte protein;SECT;T-cell serine protease 1-3E
Extra Details:: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]