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  2. Monoclonal

GTX01457

CD27 antibody [O323]

Cannot supply to this region.

SKU:
GTX01457
Additional Names:
CD27 molecule , CD27 , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55
Application:
Flow Cytometry
Concentration:
0.5 mg/ml
Physical State:
Liquid
Purification:
Affinity Purified
Storage Conditions:
2-8[o]C
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
10mM NaH₂PO₄, 150mM NaCl, 0.09% Sodium azide.
Immunogen:
CD27 molecule
Clone:
O323
Uniprot:
P26842
Synonyms:
CD27 antigen;CD27L receptor;S152;S152. LPFS2;T cell activation antigen S152;T-cell activation antigen CD27;T14;TNFRSF7;Tp55;Tumor necrosis factor receptor superfamily member 7;tumor necrosis factor receptor superfamily, member 7
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice