GTX00897
HP1 alpha antibody
Cannot supply to this region.
- SKU:
- GTX00897
- Additional Names:
- chromobox 5 , CBX5 , HEL25 , HP1 , HP1A , HP1 alpha
- Application:
- WB, IF, ICC
- Concentration:
- 0.37 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Filter-sterilized 0.12M Sodium Phosphate, 50% Glycerol, no preservatives.
- Immunogen:
- The product is prepared by immunizing rabbit with the synthetic peptide CEDAENKEKETAKS corresponding to the amino acid sequence 179-191 of human HP1 alpha
- Uniprot:
- P45973
- Synonyms:
- antigen p25;chromobox homolog 5 (HP1 alpha homolog, Drosophila);chromobox protein homolog 5;epididymis luminal protein 25;HEL25;heterochromatin protein 1 homolog alpha;heterochromatin protein 1-alpha;HP1;HP1 alpha homolog;HP1-ALPHA;HP1A;HP1Hs alpha
- Extra Details:
- This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice