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![POLH antibody [5H10]](https://www.genetex.com/upload/website/prouct_img/normal/GTX00871/GTX00871_20200406_AP_002_84_w_23053121_631.webp)
GTX00871
POLH antibody [5H10]
Cannot supply to this region.
- SKU:
- GTX00871
- Additional Names:
- DNA polymerase eta , POLH , RAD30 , RAD30A , XPV
- Application:
- WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Filter-sterilized PBS, 50% Glycerol, no preservatives.
- Immunogen:
- Human recombinant full-size Pol eta tagged with His6
- Clone:
- 5h10
- Uniprot:
- Q9Y253
- Synonyms:
- DNA polymerase eta;polymerase (DNA directed), eta;polymerase (DNA) eta;RAD30;RAD30 homolog A;RAD30A;xeroderma pigmentosum variant type protein;XP-V;XPV
- Extra Details:
- This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
- Shipping Conditions:
- Blue Ice