HDAC3 antibody [GT1144]

Cannot supply to this region.

SKU:: GTX00834
Additional Names:: histone deacetylase 3 , HD3 , KDAC3 , RPD3 , RPD3-2
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: A synthesized peptide derived from hmuan HDAC3
Clone:: GT1144
Uniprot:: O15379
Synonyms:: HD3;histone deacetylase 3;KDAC3;RPD3;RPD3-2;SMAP45
Extra Details:: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]