GTX00736
CBX1 / HP1 beta antibody
Cannot supply to this region.
- SKU:
- GTX00736
- Additional Names:
- chromobox 1 , CBX , HP1-BETA , HP1Hs-beta , HP1Hsbeta , M31 , MOD1 , p25beta
- Application:
- ChIP, WB, IF, ICC
- Concentration:
- 0.44 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Hamster, Human
- Buffer:
- Filter-sterilized 0.12M Sodium Phosphate, 50% Glycerol, no preservatives.
- Immunogen:
- synthetic peptide CNEDDDKKDDKN including the C-terminal sequence (176-185) of human HP1beta
- Uniprot:
- P83916
- Synonyms:
- CBX;chromobox homolog 1 (HP1 beta homolog Drosophila );chromobox protein homolog 1;heterochromatin protein 1 homolog beta;heterochromatin protein 1-beta;Heterochromatin protein p25;heterochromatin protein p25 beta;HP1 beta homolog;HP1-BETA;HP1Hs-beta;HP1Hsbeta;M31;MOD1;modifier 1 protein;p25beta
- Extra Details:
- This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice