GTX00721
Rad51 antibody
Cannot supply to this region.
- SKU:
- GTX00721
- Additional Names:
- RAD51 recombinase , BRCC5 , FANCR , HRAD51 , HsRad51 , HsT16930 , MRMV2 , RAD51A , RECA
- Application:
- WB, IF, ICC, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Chicken/Avian
- Reactivities:
- Fish, Hamster, Human, Mouse, Rat
- Buffer:
- 20mM Phosphate, 100mM NaCl, 50% Glycerol, no preservatives.
- Immunogen:
- Recombinant full-size human red51 protein, no tag peptide attached.
- Uniprot:
- Q06609
- Synonyms:
- BRCA1/BRCA2-containing complex, subunit 5;BRCC5;DNA repair protein RAD51 homolog 1;FANCR;HRAD51;HsRad51;HsT16930;MRMV2;RAD51 homolog A;RAD51A;RECA;RecA-like protein;RecA, E. coli, homolog of;recombination protein A
- Extra Details:
- The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
- Shipping Conditions:
- Blue Ice