KIR3DL1 antibody [6D9A4]

Cannot supply to this region.

SKU:: GTX00648
Additional Names:: CD158E1 , KIR , KIR3DL1 , KIR3DL1/S1 , KIR3DL2 , NKAT3 , NKB1 , NKB1B , killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1
Application:: ELISA, Flow Cytometry, WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Rat
Buffer:: PBS, 0.05% Sodium azide.
Immunogen:: Purified recombinant fragment of human KIR3DL1 (AA: extra 22-340) expressed in HEK293 cells.
Clone:: 6D9A4
Uniprot:: P43629
Synonyms:: CD158 antigen-like family member E;CD158E1;HLA-BW4-specific inhibitory NK cell receptor;killer cell immunoglobulin-like receptor 3DL1;killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1;KIR;KIR antigen 3DL1;KIR2DL5B;KIR3DL1/S1;MHC class I NK cell receptor;natural killer-associated transcript 3;NKAT-3;NKAT3;NKB1;NKB1B;p70 killer cell inhibitory receptor;p70 natural killer cell receptor clones CL-2/CL-11;p70 NK receptor CL-2/CL-11
Extra Details:: Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice