GTX00572
CD105 antibody [MJ7/18]
Cannot supply to this region.
- SKU:
- GTX00572
- Additional Names:
- endoglin , AI528660 , AI662476 , CD105 , Endo , S-endoglin
- Application:
- Flow Cytometry, WB, IHC-Fr, IP
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human, Mouse
- Purification:
- Protein G Purified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Rat
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS pH 7.4, 15 mM sodium azide.
- Immunogen:
- Inflamed mouse skin
- Clone:
- MJ7/18
- Uniprot:
- Q63961
- Synonyms:
- AI528660;AI662476;CD105;cell surface MJ7/18 antigen;En;Endo;endoglin;S-endoglin;transmembrane glycoprotein
- Extra Details:
- Enables protein homodimerization activity and transforming growth factor beta binding activity. Involved in several processes, including circulatory system development; positive regulation of cell differentiation; and regulation of gene expression. Acts upstream of or within angiogenesis; cell migration involved in endocardial cushion formation; and positive regulation of angiogenesis. Located in endothelial microparticle. Is expressed in several structures, including aorta-gonad-mesonephros; brain; cardiovascular system; extraembryonic component; and liver. Used to study arteriovenous malformations of the brain and hereditary hemorrhagic telangiectasia. Human ortholog(s) of this gene implicated in artery disease (multiple); breast cancer; hemangioma (multiple); and hereditary hemorrhagic telangiectasia. Orthologous to human ENG (endoglin). [provided by Alliance of Genome Resources, Jul 2025]
- Shipping Conditions:
- Blue Ice