Siglec-5 antibody [1A5] (PE)

Cannot supply to this region.

SKU:: GTX00537-08
Additional Names:: CD170 , CD33L2 , OBBP2 , SIGLEC5 , sialic acid binding Ig like lectin 5
Application:: Flow Cytometry
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C Do not freeze. Protect from light.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Fusion protein composed of human CD170 extracellular domain and Fc region of human IgG1
Clone:: 1A5
Uniprot:: O15389
Synonyms:: CD170;CD33 antigen-like 2;CD33L2;OB-binding protein 2;OB-BP2;OBBP2;obesity-binding protein 2;sialic acid-binding Ig-like lectin 5;sialic acid-binding immunoglobulin-like lectin 5;SIGLEC-5
Extra Details:: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]