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  2. Monoclonal

GTX00536

CCR3 antibody [5E8]

Cannot supply to this region.

SKU:
GTX00536
Additional Names:
CC motif chemokine receptor 3 , CCCKR3 , CCR3 , CD193 , CKR3 , CMKBR3 , C-C motif chemokine receptor 3
Application:
Flow Cytometry
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
C-C motif chemokine receptor 3
Clone:
5E8
Uniprot:
P51677
Synonyms:
b-chemokine receptor;C C CKR3;C-C chemokine receptor type 3;C-C CKR-3;CC chemokine receptor 3;CC-CKR-3;CCR-3;CD193;chemokine (C-C motif) receptor 3;CKR 3;CKR3;CMKBR3;eosinophil CC chemokine receptor 3;eosinophil eotaxin receptor
Extra Details:
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]
Shipping Conditions:
Blue Ice