ZAP70 antibody [ZAP-03]

Cannot supply to this region.

SKU:: GTX00530
Additional Names:: ADMIO2 , IMD48 , SRK , STCD , STD , TZK , ZAP70 , zeta chain of T cell receptor associated protein kinase 70
Application:: Flow Cytometry, WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Bacterially expressed fusion protein representing C-terminal part (160 amino acids) of human ZAP70 with histidine tag
Clone:: ZAP-03
Uniprot:: P43403
Synonyms:: 70 kDa zeta-associated protein;70 kDa zeta-chain associated protein;ADMIO2;IMD48;SRK;STCD;STD;syk-related tyrosine kinase;tyrosine-protein kinase ZAP-70;TZK;ZAP-70;zeta chain of T cell receptor associated protein kinase 70kDa;zeta-chain (TCR) associated protein kinase 70kDa;zeta-chain associated protein kinase, 70kD
Extra Details:: This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice