GRB2 antibody [polyclonal antibody (554)]

Cannot supply to this region.

SKU:: GTX00529
Additional Names:: ASH , EGFRBPGRB2 , GRB2 , Grb33 , MST084 , MSTP084 , NCKAP2 , growth factor receptor bound protein 2
Application:: WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
Uniprot:: P62993
Synonyms:: abundant SRC homology;Adapter protein GRB2;ASH;EGFRBP-GRB2;epidermal growth factor receptor-binding protein GRB2;epididymis secretory sperm binding protein;Grb3-3;growth factor receptor-bound protein 2;growth factor receptor-bound protein 3;HT027;MST084;MSTP084;NCKAP2;protein Ash;SH2/SH3 adapter GRB2
Extra Details:: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]