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  2. Monoclonal

GTX00514

Nectin 1 antibody [R1.302]

Cannot supply to this region.

SKU:
GTX00514
Additional Names:
CD111 , CLPED1 , ED4 , HIgR , HV1S , HVEC , NECTIN1 , OFC7 , PRR , PRR1 , PVRL1 , PVRR , PVRR1 , SK12 , nectin cell adhesion molecule 1 , nectin1 , Nectin 1
Application:
Flow Cytometry, IHC, WB, IF, ICC, IP
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Protein A Purified
Storage Conditions:
2-8[o]C Do not freeze.
Supplier:
Genetex
Host:
Mouse
Reactivities:
Human
Buffer:
PBS, 15mM Sodium azide.
Immunogen:
NIH/3T3 cells transfected with human CD111
Clone:
R1.302
Uniprot:
Q15223
Synonyms:
CD111;CLPED1;ectodermal dysplasia 4 (Margarita Island type);ED4;herpes simplex virus type 1 sensitivity;herpes virus entry mediator C;herpesvirus Ig-like receptor;HIgR;HV1S;HVEC;nectin 1;Nectin cell adhesion molecule 1;nectin-1;OFC7;poliovirus receptor-like 1;poliovirus receptor-related 1 (herpesvirus entry mediator C);poliovirus receptor-related protein 1;PRR;PRR1;PVRL1;PVRR;PVRR1;SK-12
Extra Details:
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009]
Shipping Conditions:
Blue Ice