uPAR antibody [VIM5]

Cannot supply to this region.

SKU:: GTX00512
Additional Names:: CD87 , PLAUR , UPAR , URKR , plasminogen activator, urokinase receptor , uPA Receptor , uPAR
Application:: Flow Cytometry
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Protein A Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 15mM Sodium azide.
Immunogen:: human myeloid cell line THP-1
Clone:: VIM5
Uniprot:: Q03405
Synonyms:: CD87;monocyte activation antigen Mo3;U-PAR;u-plasminogen activator receptor form 2;UPAR;URKR;urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
Extra Details:: This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice