GTX00512-08
uPAR antibody [VIM5] (PE)
Cannot supply to this region.
- SKU:
- GTX00512-08
- Additional Names:
- CD87 , PLAUR , UPAR , URKR , plasminogen activator, urokinase receptor , uPA Receptor , uPAR
- Application:
- Flow Cytometry
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Size-exclusion Chromatography
- Storage Conditions:
- 2-8[o]C Do not freeze. Protect from light.
- Supplier:
- Genetex
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- PBS, 15mM Sodium azide.
- Immunogen:
- human myeloid cell line THP-1
- Clone:
- VIM5
- Uniprot:
- Q03405
- Synonyms:
- CD87;monocyte activation antigen Mo3;U-PAR;u-plasminogen activator receptor form 2;UPAR;URKR;urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
- Extra Details:
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice