CD160 antibody [BY55]

Cannot supply to this region.

SKU:: GTX00488
Additional Names:: BY55 , CD160 , CD160 molecule , NK1 , NK28
Application:: Flow Cytometry, IP
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: 2-8[o]C Do not freeze.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: TBS, 15mM Sodium azide.
Immunogen:: Human NK cell line YT2C2
Clone:: BY55
Uniprot:: O95971
Synonyms:: BY55;CD160 antigen;CD160-delta Ig;natural killer cell receptor BY55;natural killer cell receptor, immunoglobulin superfamily member;NK1;NK28
Extra Details:: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice