Human STIP1 protein, His tag (active)

Cannot supply to this region.

SKU:: GTX00445-PRO
Additional Names:: stress induced phosphoprotein 1 , HEL-S-94n , HOP , IEF-SSP-3521 , P60 , STI1 , STI1L
Application:: FuncS
Physical State:: Liquid
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:: Genetex
Buffer:: 20mM HEPES, 80mM NaCl, 10% Glycerol, no preservatives.
Immunogen:: stress induced phosphoprotein 1
Species:: Human
Uniprot:: P31949
Synonyms:: calgizzarin;epididymis secretory protein Li 43;epididymis secretory sperm binding protein Li 94n;HEL-S-43;HEL-S-94n;HOP;hsc70/Hsp90-organizing protein;Hsp70/Hsp90-organizing protein;IEF-SSP-3521;metastatic lymph node gene 70 protein;MLN 70;MLN70;NY-REN-11 antigen;P60;protein S100-A11;protein S100-C;renal carcinoma antigen NY-REN-11;S100 calcium-binding protein A11;S100C;STI1;STI1L;stress-induced-phosphoprotein 1;transformation-sensitive protein IEF SSP 3521
Extra Details:: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]