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GTX00214-PRO

Human CX3CL1 protein, His tag (active)

Cannot supply to this region.

SKU:
GTX00214-PRO
Additional Names:
C-X3-C motif chemokine ligand 1 , ABCD-3 , C3Xkine , CXC3 , CXC3C , NTN , NTT , SCYD1 , fractalkine , neurotactin
Application:
FuncS
Physical State:
Lyophilized
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Buffer:
Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Immunogen:
C-X3-C motif chemokine ligand 1
Species:
Human
Uniprot:
P78423
Synonyms:
ABCD-3;C-X3-C motif chemokine 1;C3Xkine;chemokine (C-X3-C motif) ligand 1;CX3C membrane-anchored chemokine;CXC3;CXC3C;fractalkine;neurotactin;NTN;NTT;SCYD1;small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin);small inducible cytokine subfamily D (Cys-X3-Cys), member-1;small-inducible cytokine D1
Extra Details:
This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
Shipping Conditions:
Blue Ice