Human TGF beta 2 protein, His tag (active)

Cannot supply to this region.

SKU:: GTX00211-PRO
Additional Names:: transforming growth factor beta 2 , G-TSF , LDS4 , TGF-beta2
Application:: FuncS
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Immunogen:: transforming growth factor beta 2
Species:: Human
Uniprot:: P61812
Synonyms:: BSC-1 cell growth inhibitor;cetermin;G-TSF;glioblastoma-derived T-cell suppressor factor;LDS4;polyergin;prepro-transforming growth factor beta-2;TGF-beta2;transforming growth factor beta-2 proprotein
Extra Details:: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]

Shipping Conditions:: Blue Ice