Human Caspase 3 protein, His tag

Cannot supply to this region.

SKU:: GTX00207-PRO
Additional Names:: caspase 3 , CPP32 , CPP32B , SCA-1
Application:: FuncS
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
Immunogen:: caspase 3
Species:: Human
Uniprot:: p42574
Synonyms:: apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP-32;CPP32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1
Extra Details:: The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]