GTX00188-PRO
Human DKK1 protein, His tag
Cannot supply to this region.
- SKU:
- GTX00188-PRO
- Additional Names:
- dickkopf WNT signaling pathway inhibitor 1 , DKK-1 , SK
- Application:
- FuncS
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 10mM PBS (pH7.4) to 0.1-1.0mg/ml. Do not vortex. Lyophilized from PBS (pH7.4), 0.01% SKL, 1mM DTT, 5% Trehalose, ProClin 300.
- Immunogen:
- dickkopf WNT signaling pathway inhibitor 1
- Species:
- Human
- Uniprot:
- O94907
- Synonyms:
- dickkopf 1 homolog;dickkopf-1 like;dickkopf-like protein 1;dickkopf-related protein 1;DKK-1;SK
- Extra Details:
- This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]
- Shipping Conditions:
- Blue Ice