GTX00138-PRO
Human IL24 protein, His tag (active)
Cannot supply to this region.
- SKU:
- GTX00138-PRO
- Additional Names:
- interleukin 24 , C49A , FISP , IL10B , MDA7 , MOB5 , ST16
- Application:
- FuncS
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 20mM Tris and 150mM NaCl to 0.1-1.0mg/ml. Do not vortex. Lyophilized from 20mM Tris, 150mM NaCl, 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose, ProClin 300.
- Immunogen:
- interleukin 24
- Species:
- Human
- Uniprot:
- Q13007
- Synonyms:
- C49A;FISP;IL-4-induced secreted protein;IL10B;interleukin-24;MDA7;melanocyte-associated Mda-7;melanoma differentiation-associated gene 7 protein;MOB5;ST16;suppression of tumorigenicity 16 (melanoma differentiation);Suppression of tumorigenicity 16 protein
- Extra Details:
- This gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice