Human CCL5 Protein

Size

£497.00

SKU:: PME30079
Additional Names:: C-C Motif Chemokine 5;EoCP;Eosinophil Chemotactic Cytokine;SIS-Delta;Small-Inducible Cytokine A5;T Cell-Specific Protein P228;TCP228;T-Cell-Specific Protein RANTES;CCL5;D17S136E;SCYA5
Molecular Weight:: 7.8 KDa
Purity:: Greater than 95% as determined by reducing SDS-PAGE.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Target:: CCL5
Not available:: Not available
Extra Details:: Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1; CCR3; CCR4; and CCR5. N-Terminal truncated CCL5/RANTES; Met-RANTES; and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.