PME30059
Human pro-Beta NGF Protein
Size
£457.00
- SKU:
- PME30059
- Additional Names:
- Beta-Nerve Growth Factor;Beta-NGF;NGF;NGFB;-NGF;pro-Beta NGF
- Molecular Weight:
- 25 KDa
- Purity:
- Greater than 95% as determined by reducing SDS-PAGE.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl;500mM NaCl;5%Trehalose;5%Mannitol;0.01%tween80;1mM EDTA;pH8.0.
- Target:
- pro-Beta
- Not available:
- Not available
- Extra Details:
- The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges; whereas proneurotrophins and mature neurotrophins elicit opposite biological effects. ProNGF functions preferentially via the complex of pan-neurotrophin receptor p75 (p75NTR) and vps10p domain-containing receptor sortilin inducing neuronal apoptosis and contributing to age- and disease-related neurodegeneration.
- Shipping Conditions:
- Ambient