Human CCL11 Protein

Size

£423.00

SKU:: PME30053
Additional Names:: Eotaxin;C-C Motif Chemokine 11;Eosinophil Chemotactic Protein;Small-Inducible Cytokine A11;CCL11;SCYA11
Molecular Weight:: 8.56 KDa
Purity:: Greater than 95% as determined by reducing SDS-PAGE.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.4.
Target:: CCL11
Not available:: Not available
Extra Details:: C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens; CCL11 selectively recruits eosinophils; a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2; CCR3 and CCR5. However; it has been found that CCL11 has high degree selectivity for its receptor; such that they are inactive on neutrophils and monocytes; which do not express CCR3.