Human/Mouse/Rat GDF-8 Protein

Size

£984.00

SKU:: PME30029
Additional Names:: Growth/differentiation factor 8;GDF-8;Myostatin;Mstn;Gdf8
Molecular Weight:: 13.1 KDa
Purity:: Greater than 95% as determined by reducing SDS-PAGE.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from a 0.2 μm filtered solution of PBS; pH 7.4.
Target:: GDF-8
Not available:: Not available
Extra Details:: Growth/differentiation factor 8(Mstn; GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer; and interacts with WFIKKN2; leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.