PME30015
Human PDGF-BB Protein
Size
£599.00
- SKU:
- PME30015
- Additional Names:
- PDGFBB;PDGF-BB
- Molecular Weight:
- 12.42 KDa
- Purity:
- Greater than 98% as determined by reducing SDS-PAGE.
- Storage Conditions:
- Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Supplier:
- DIMA Biotechnology Ltd
- Formulation:
- Lyophilized from a 0.2 μm filtered solution of 20mM NaAc-HAc; pH 4.5.
- Target:
- PDGF-BB
- Not available:
- Not available
- Extra Details:
- Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB); where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition; PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
- Shipping Conditions:
- Ambient