Human M-CSF (C-6His) Protein

Size

£599.00

SKU:: PME30008
Additional Names:: Macrophage Colony-Stimulating Factor 1;CSF-1;M-CSF;MCSF;Lanimostim;CSF1
Molecular Weight:: 26.17 KDa
Purity:: Greater than 95% as determined by reducing SDS-PAGE.
Storage Conditions:: Store at -20[o]C to -80[o]C for 12 months in lyophilized form. After reconstitution; if not intended for use within a month; aliquot and store at -80[o]C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Supplier:: DIMA Biotechnology Ltd
Formulation:: Lyophilized from a 0.2 μm filtered solution of 20mM PB; 150mM NaCl; pH 7.2.
Target:: M-CSF
Not available:: Not available
Extra Details:: Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production; differentiation; and function of 2 related white cell populations of the blood; the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines; and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation; the regulation of bone resorption; and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton; regulates formation of membrane ruffles; cell adhesion and cell migration. it also plays a role in lipoprotein clearance.